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1

“Disease modifying nutricals” for multiple sclerosis

Schmitz, Katja, Barthelmes, Julia, Stolz, Leonie, Beyer, Susanne, Diehl, Olaf, Tegeder, Irmgard

Journal:

Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 2.14 MB

english, 2015

2

Gαq/11 signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization

Anke Tappe-Theodor, Cristina E. Constantin, Irmgard Tegeder, Stefan G. Lechner, Michiel Langeslag, Peter Lepcynzsky, Richard I. Wirotanseng, Martina Kurejova, Nitin Agarwal, Gergely Nagy, Andrew Todd,

Journal:

Year:

2012

Language:

english

File:

PDF, 1.53 MB

english, 2012

3

Pharmacokinetics of Opioids in Liver Disease

Irmgard Tegeder, Jörn Lötsch, Dr Gerd Geisslinger

Journal:

Clinical Pharmacokinetics

Year:

1999

Language:

english

File:

PDF, 294 KB

english, 1999

4

Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain

Valek, Lucie, Häussler, Annett, Dröse, Stefan, Eaton, Philipp, Schröder, Katrin, Tegeder, Irmgard

Journal:

Year:

2017

Language:

english

File:

PDF, 2.89 MB

english, 2017

5

Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype

Irmgard Tegeder, Jan Adolph, Helmut Schmidt, Clifford J. Woolf, Gerd Geisslinger, Jörn Lötsch

Journal:

European Journal of Pain

Year:

2008

Language:

english

File:

PDF, 325 KB

english, 2008

6

Comparison of nociceptive behavior in prostaglandin E, F, D, prostacyclin and thromboxane receptor knockout mice

Laura Popp, Annett Häussler, Anke Olliges, Rolf Nüsing, Shuh Narumiya, Gerd Geisslinger, Irmgard Tegeder

Journal:

European Journal of Pain

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

7

Opioid-mediated drug actions cannot be concluded from naloxone induced reversal of anti-nociceptive effects in behavioural tests only

Jörn Lötsch, Irmgard Tegeder

Journal:

European Journal of Pain

Year:

2010

Language:

english

File:

PDF, 264 KB

english, 2010

8

Determination of 8-methoxypsoralen in human plasma, and microdialysates using liquid chromatography–tandem mass spectrometry

Lutz Bräutigam, Maic Seegel, Irmgard Tegeder, Helmut Schmidt, Silke Meier, Maurizio Podda, Roland Kaufmann, Marcella Grundmann-Kollmann, Gerd Geisslinger

Journal:

Journal of Chromatography B

Year:

2003

Language:

english

File:

PDF, 170 KB

english, 2003

9

Determination of celecoxib in human plasma and rat microdialysis samples by liquid chromatography tandem mass spectrometry

Lutz Bräutigam, Gregor Vetter, Irmgard Tegeder, Georg Heinkele, Gerd Geisslinger

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 255 KB

english, 2001

10

Validation of a new fluorogenic real-time PCR assay for detection of CYP2C9 allelic variants and CYP2C9 allelic distribution in a German population

Maria Burian, Sabine Grösch, Irmgard Tegeder, Gerd Geisslinger

Journal:

British Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 90 KB

english, 2002

11

Spatial distribution of 8-methoxypsoralen penetration into human skin after systemic or topical administration

Marcella Grundmann-Kollmann, Maurizio Podda, Lutz Bräutigam, Katja Hardt-Weinelt, Ralf J. Ludwig, Gerd Geisslinger, Roland Kaufmann, Irmgard Tegeder

Journal:

British Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 94 KB

english, 2002

12

Inhibition of Noxious Stimulus-Induced Spinal Prostaglandin E2 Release by Flurbiprofen Enantiomers : A Microdialysis Study

Gerd Geisslinger, Uta Muth-Selbach, Ovidiu Coste, Gregor Vetter, Andreas Schrödter, Hans-Georg Schaible, Kay Brune, Irmgard Tegeder

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000

13

Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E2 release in the spinal cord

Irmgard Tegeder, Ellen Niederberger, Gregor Vetter, Lutz Bräutigam, Gerd Geisslinger

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 1.82 MB

english, 2001

14

Increased CNS uptake and enhanced antinociception of morphine-6-glucuronide in rats after inhibition of P-glycoprotein

Jörn Lötsch, Rodolfo Schmidt, Gregor Vetter, Helmut Schmidt, Ellen Niederberger, Gerd Geisslinger, Irmgard Tegeder

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 303 KB

english, 2002

15

Protein associated with Myc (PAM) is involved in spinal nociceptive processing

Corina Ehnert, Irmgard Tegeder, Sandra Pierre, Kerstin Birod, Hong-Van Nguyen, Achim Schmidtko, Gerd Geisslinger, Klaus Scholich

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 484 KB

english, 2004

16

The role of cGMP and PKG-I in spinal nociceptive processing

Achim Schmidtko, Irmgard Tegeder, Ellen Niederberger, Franz Hofmann, Peter Ruth, Gerd Geisslinger

Journal:

BMC Pharmacology

Year:

2005

Language:

english

File:

PDF, 205 KB

english, 2005

17

cGMP-dependent signaling pathways in spinal pain processing

Achim Schmidtko, Wei Gao, Peter König, Sandra Heine, Matthias Sausbier, Peter Ruth, Doris Koesling, Irmgard Tegeder, Andreas Friebe, Gerd Geisslinger

Journal:

BMC Pharmacology

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

18

Cardiovascular risk with cyclooxygenase inhibitors: general problem with substance specific differences?

Irmgard Tegeder, Gerd Geisslinger

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2006

Language:

english

File:

PDF, 350 KB

english, 2006

19

Emerging country pharmacology: a 10-year perspective fromNaunyn-Schmiedeberg’s Archives of Pharmacology

Marcio M. Coelho, Irmgard Tegeder, Martin C. Michel

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

20

Einsatz von Opioiden bei Leber- oder Niereninsuffizienz

Irmgard Tegeder, G. Geisslinger, J. Lötsch

Journal:

Year:

1999

Language:

german

File:

PDF, 191 KB

german, 1999

21

Simultaneous fitting of R- and S-ibuprofen plasma concentrations after oral administration of the racemate

Jörn Lötsch, Uta Muth-Selbach, Irmgard Tegeder, Kay Brune, Gerd Geisslinger

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 576 KB

english, 2001

22

Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats

Charles Mills, Milan Makwana, Adam Wallace, Susanna Benn, Helmut Schmidt, Irmgard Tegeder, Michael Costigan, Robert H Brown Jr, Gennadij Raivich, Clifford J. Woolf

Journal:

European Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 737 KB

english, 2008

23

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

Tegeder, Irmgard, Costigan, Michael, Griffin, Robert S, Abele, Andrea, Belfer, Inna, Schmidt, Helmut, Ehnert, Corina, Nejim, Jemiel, Marian, Claudiu, Scholz, Joachim

Journal:

Nature Medicine

Year:

2006

Language:

english

File:

PDF, 510 KB

english, 2006

24

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

Agarwal, Nitin, Pacher, Pal, Tegeder, Irmgard, Amaya, Fumimasa, Constantin, Cristina E, Brenner, Gary J, Rubino, Tiziana, Michalski, Christoph W, Marsicano, Giovanni, Monory, Krisztina

Journal:

Nature Neuroscience

Year:

2007

Language:

english

File:

PDF, 604 KB

english, 2007

25

Comparison of Tissue Concentrations After Intramuscular and Topical Administration of Ketoprofen

Irmgard Tegeder, Jörn Lötsch, Martina Kinzig-Schippers, Fritz Sörgel, Gary R. Kelm, Stephen T. Meller, Gerd Geisslinger

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001

26

Pathophysiology and treatment of pain in joint disease

Hans-Georg Schaible, Martin Schmelz, Irmgard Tegeder

Journal:

Advanced Drug Delivery Reviews

Year:

2006

Language:

english

File:

PDF, 242 KB

english, 2006

27

Analgesic efficacy of tramadol, pregabalin and ibuprofen in menthol-evoked cold hyperalgesia

Kosta Altis, Achim Schmidtko, Carlo Angioni, Karina Kuczka, Helmut Schmidt, Gerd Geisslinger, Jörn Lötsch, Irmgard Tegeder

Journal:

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009

28

Genetic modulation of the pharmacological treatment of pain

Jörn Lötsch, Gerd Geisslinger, Irmgard Tegeder

Journal:

Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 679 KB

english, 2009

29

Expression of rat liver long-chain acyl-CoA synthetase and characterization of its role in the metabolism of R-ibuprofen and other fatty acid-like xenobiotics

Roland Bruggera, Christine Reichel, Begonia Garcia Alia, Kay Brune, Tokuo Yamamoto, Irmgard Tegeder, Gerd Geissinger

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 199 KB

english, 2001

30

Current evidence for a modulation of low back pain by human genetic variants

Irmgard Tegeder, Jörn Lötsch

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 520 KB

english, 2009

31

Progranulin contributes to endogenous mechanisms of pain defense after nerve injury in mice

Hee-Young Lim, Boris Albuquerque, Annett Häussler, Thekla Myrczek, Aihao Ding, Irmgard Tegeder

Journal:

Journal of Cellular and Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 797 KB

english, 2012

32

The impact of CREB and its phosphorylation at Ser142 on inflammatory nociception

Ellen Niederberger, Corina Ehnert, Wei Gao, Ovidiu Coste, Achim Schmidtko, Laura Popp, Charlotte von Gall, Horst Werner Korf, Irmgard Tegeder, Gerd Geisslinger

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 367 KB

english, 2007

33

Inhibitor Kappa B Kinase Beta Dependent Cytokine Upregulation in Nociceptive Neurons Contributes to Nociceptive Hypersensitivity After Sciatic Nerve Injury

Maike Kanngiesser, Annett Häussler, Thekla Myrczek, Nele Küsener, Hee-Young Lim, Gerd Geisslinger, Ellen Niederberger, Irmgard Tegeder

Journal:

The Journal of Pain

Year:

2012

Language:

english

File:

PDF, 1.42 MB

english, 2012

34

Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve

Reynir Scheving, Ilka Wittig, Heinrich Heide, Boris Albuquerque, Mirco Steger, Ulrich Brandt, Irmgard Tegeder

Journal:

Journal of Proteomics

Year:

2012

Language:

english

File:

PDF, 971 KB

english, 2012

35

Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk

Alexandra Doehring, Charalambos Antoniades, Keith M. Channon, Irmgard Tegeder, Jörn Lötsch

Journal:

Mutation Research/Reviews in Mutation Research

Year:

2008

Language:

english

File:

PDF, 786 KB

english, 2008

36

Comparative proteomic analysis of the rat spinal cord in inflammatory and neuropathic pain models

Susanne Kunz, Irmgard Tegeder, Ovidiu Coste, Claudiu Marian, Anja Pfenninger, Carsten Corvey, Michael Karas, Gerd Geisslinger, Ellen Niederberger

Journal:

Neuroscience Letters

Year:

2005

Language:

english

File:

PDF, 183 KB

english, 2005

37

The calpain inhibitor MDL 28170 prevents inflammation-induced neurofilament light chain breakdown in the spinal cord and reduces thermal hyperalgesia

Susanne Kunz, Ellen Niederberger, Corina Ehnert, Ovidiu Coste, Anja Pfenninger, Jochen Kruip, Thomas M Wendrich, Achim Schmidtko, Irmgard Tegeder, Gerd Geisslinger

Journal:

Year:

2004

Language:

english

File:

PDF, 471 KB

english, 2004

38

Essential role of the synaptic vesicle protein synapsin II in formalin-induced hyperalgesia and glutamate release in the spinal cord

Achim Schmidtko, Domenico Del Turco, Ovidiu Coste, Corina Ehnert, Ellen Niederberger, Peter Ruth, Thomas Deller, Gerd Geisslinger, Irmgard Tegeder

Journal:

Year:

2005

Language:

english

File:

PDF, 726 KB

english, 2005

39

Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in rats

Joachim Scholz, Andrea Abele, Claudiu Marian, Annett Häussler, Teri A. Herbert, Clifford J. Woolf, Irmgard Tegeder

Journal:

Year:

2008

Language:

english

File:

PDF, 2.76 MB

english, 2008

40

Genetic deletion of synapsin II reduces neuropathic pain due to reduced glutamate but increased GABA in the spinal cord dorsal horn

Achim Schmidtko, Ceng Luo, Wei Gao, Gerd Geisslinger, Rohini Kuner, Irmgard Tegeder

Journal:

Year:

2008

Language:

english

File:

PDF, 766 KB

english, 2008

41

No NO, no pain? The role of nitric oxide and cGMP in spinal pain processing

Achim Schmidtko, Irmgard Tegeder, Gerd Geisslinger

Journal:

Trends in Neurosciences

Year:

2009

Language:

english

File:

PDF, 363 KB

english, 2009

42

Antinociceptive effects of morphne-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test

Jörn Lötsch, Irmgard Tegeder, Martin S Angst, Gerd Geisslinger

Journal:

Year:

2000

Language:

english

File:

PDF, 856 KB

english, 2000

43

The influence of inhibition of probenecid sensitive transporters on the central nervous system (CNS) uptake and the antinociceptive activity of morphine-6-glucuronide in rats

Jörn Lötsch, Rodolfo Schmidt, Gregor Vetter, Helmut Schmidt, Carsten Skarke, Ellen Niederberger, Gerd Geisslinger, Irmgard Tegeder

Journal:

Neuroscience Letters

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

44

Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats

Irmgard Tegeder, Achim Schmidtko, Ellen Niederberger, Peter Ruth, Gerd Geisslinger

Journal:

Neuroscience Letters

Year:

2002

Language:

english

File:

PDF, 187 KB

english, 2002

45

Differential effect of selective cyclooxygenase-2 (COX-2) inhibitor NS 398 and diclofenac on formalin-induced nociception in the rat

Christian Euchenhofer, Christian Maihöfner, Kay Brune, Irmgard Tegeder, Gerd Geisslinger

Journal:

Neuroscience Letters

Year:

1998

Language:

english

File:

PDF, 65 KB

english, 1998

46

Release of glutamate, nitric oxide and prostaglandin E2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation

Gregor Vetter, Gerd Geisslinger, Irmgard Tegeder

Journal:

Year:

2001

Language:

english

File:

PDF, 142 KB

english, 2001

47

Inhibition of cyclic guanosine 5′-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation

Achim Schmidtko, Peter Ruth, Gerd Geisslinger, Irmgard Tegeder

Journal:

Year:

2003

Language:

english

File:

PDF, 257 KB

english, 2003

48

Inhibition of GTP cyclohydrolase reduces cancer pain in mice and enhances analgesic effects of morphine

Pickert, Geethanjali, Myrczek, Thekla, Rückert, Steven, Weigert, Andreas, Häussler, Annett, Ferreirós, Nerea, Brüne, Bernhard, Lötsch, Jörn, Tegeder, Irmgard

Journal:

Journal of Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

49

GCH1 Haplotype Determines Vascular and Plasma Biopterin Availability in Coronary Artery Disease: Effects on Vascular Superoxide Production and Endothelial Function

Charalambos Antoniades, Cheerag Shirodaria, Tim Van Assche, Colin Cunnington, Irmgard Tegeder, Jörn Lötsch, Tomasz J. Guzik, Paul Leeson, Jonathan Diesch, Dimitris Tousoulis, Christodoulos Stefanadis,

Journal:

Journal of the American College of Cardiology

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

50

Peripheral nerve injury produces a sustained shift in the balance between glutamate release and uptake in the dorsal horn of the spinal cord

Perrine Inquimbert, Karsten Bartels, Olusegun B. Babaniyi, Lee B. Barrett, Irmgard Tegeder, Joachim Scholz

Journal:

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

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